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August 13, 2023

Sebaceous Carcinoma

mature couple with no skin cancer

What is Sebaceous Carcinoma?

Sebaceous carcinoma, pronounced “suh-BAY-shus,” emerges as a rare skin cancer originating from oil-producing glands within the skin. These sebaceous glands, responsible for producing protective sebum, can be found extensively beneath the skin’s surface, especially in areas with hair.

While it predominantly targets the eyelids, sebaceous carcinoma can develop anywhere on the body. Its aggressive nature is evident through rapid spread, classifying it as metastatic cancer when it extends beyond the initial site.

Under various aliases like sebaceous gland carcinoma or meibomian gland carcinoma, it’s a formidable adversary seldom seen, affecting a mere 1% of eyelid tumors and presenting unique challenges in diagnosis and treatment.

dermatologist-examining-skin-patient-with-dermatoscope

What are the causes and risk factors of Sebaceous Carcinoma?

The precise triggers behind sebaceous carcinoma’s emergence unknown. Experts are still piecing together the puzzle of its origins. However, common threads are starting to emerge. Exposure to the sun’s ultraviolet rays, similar to other skin cancers, might play a role in its development. Notably, those who have undergone radiation therapy, particularly around the head or neck, could be more susceptible.

Certain factors that can make you more likely to get sebaceous carcinoma:

Muir-Torre Syndrome: People with a rare genetic condition called Muir-Torre syndrome have a higher risk of getting sebaceous carcinoma, as well as colorectal cancer.

Asian Descent: Some studies suggest that people of Asian descent might be more vulnerable to sebaceous carcinoma.

Age: Getting older can increase the risk.

Sun Exposure: Spending a lot of time in the sun without protection can also make it more likely.

Weakened Immune System: If your immune system is weakened due to conditions like cancer, HIV/AIDS, organ transplant medications, or drugs for arthritis or psoriasis, you are at a higher risk.

What are the symptoms of Sebaceous Carcinoma?

Advanced sebaceous carcinoma reveals a range of symptoms that warrant attention. Left untreated, this aggressive skin cancer can trigger various manifestations, including:

  • Loss of eyelashes, a concerning sign of its impact on the delicate eye area.
  • Oozing growths on both upper and lower eyelids, a distressing consequence of the disease’s progression.
  • Reddish eyes that resemble conjunctivitis, a symptom that can raise alarm.
  • Vision problems, a grave concern due to the potential impairment it poses.

How is Sebaceous Carcinoma treated?

The arsenal of treatments for sebaceous carcinoma encompasses diverse strategies tailored to the individual’s condition.

Surgical avenues take the forefront:

  • Wide Local Excision: A meticulous procedure that removes the tumor and a normal tissue margin. This helps ensure the cancer’s thorough elimination.

  • Mohs Surgery: Employing a staged approach, Mohs surgery incrementally removes the cancerous tumor and surrounding healthy tissue. During the procedure, thin slices of tissue are examined to gauge the need for further excision, guaranteeing complete eradication of cancer cells.

  • Radiation Therapy: Reserved for cases where surgery isn’t feasible, radiation therapy targets the cancer cells with high-energy rays, inhibiting their growth and division.

dermatologist-doing-check-patient-with-skin-cancer

FAQ about Sebaceous Carcinoma

What distinguishes Sebaceous Carcinoma from Sebaceous Hyperplasia and Sebaceous Cysts

Sebaceous hyperplasia is a benign growth within hair follicles, while sebaceous cysts are noncancerous growths forming beneath the skin due to clogged sebaceous glands.

When should I seek medical attention for skin growths or changes?

It’s advisable to consult a healthcare provider if you notice any unusual growths on your skin, especially around the eyes, or experience changes in moles or birthmarks.

What questions should I ask my dermatologist about Sebaceous Carcinoma?

Some relevant questions include understanding the causes, potential risks, suitable treatment options, and the need for cancer screenings based on your individual circumstances.

Is there a connection between hormonal changes and the development of Sebaceous Carcinoma?

While no direct link has been established, hormonal changes might influence the risk, but more research is needed for a conclusive answer.

Is there a dermatologist near me in San Francisco that offers treatment for Sebaceous Carcinoma?

Yes. At our San Francisco dermatology office we offer treatment for Sebaceous Carcinoma to patients from San Francisco and the surrounding area. Contact our office today to schedule an appointment.